Ana Beatriz Villaseñor Altamiano

Bio

I am a Ph.D. candidate in Alejandra Medina-Rivera’s lab, the Regulatory Genomics and Bioinformatics Laboratory at International Laboratory for Human Genome Research (LIIGH) from the National Autonomous University of Mexico (UNAM). Our goal is to integrate public microarray and RNA-seq data, together with samples manually curated of lung diseases, such as Chronic Obstructive Pulmonary Disease (COPD) and Idiopatic Pulmonary Fibrosis (IPF) for better characterization of gene expression signatures. We work in close colaboration with Julio Collado-Vides, Moises Selman and Yalbi I. Balderas-Martínez.

Education

Projects

We created PulmonDB, a gene expression lung diseases database, created with public transcriptomic high-throuput data and manual curation information with an online interface for a quick accessibility.

  • Gene expression profile in COPD patients

Using PulmonDB we are analysing gene expression profiles in COPD patients to understand better the disease.

Past Projects

My project aim was to unscramble the alternative splicing effects of TCDD in C57BL6 mouse hepatocytes using high-throughput data.

I characterized the protein expression of Insulin-Like Growth Factor Binding Protein II (IGFBP2) during the develompent of cancer in rat livers using blood and tissue.

Internships

PulmonDB data analysis.

Set non-public resource to build compendia in Mexico.

Explored exon microarrays of mouse liver to characterize alternative splicing events under TCDD exposure.

Analyzed cell growth, viability, and metastasis by transfectin postate cell lines to uncover potential prostate cancer driver genes.

Seminars, conferences and workshops

  • WGCAC Next Generation Sequencing Bioinformatics Chile 2019 Workshop attendee | 2019 | Santiago, Chile

  • Statistical and Computational Challenges in High-Throughput Genomics with Application to Precision Medicine Talk | 2018 | Oaxaca, Mexico

  • American Thoracic Society 2018, International Conference Poster | 2018 | San Diego, CA

  • International Workshops on Bioinformatics-PYTHON Workshop attendee | 2017 | CCG, UNAM

Teaching

  • Ecology/R Workshop in DataCarpentry | Instructor 2018 | Universidad de Puerto Rico | 2017 | Puerto Rico, San Juan

  • International Workshops on Bioinformatics-GALAXY Teacher Assistant | Universidad Nacional Autonoma de México | 2017 | México, CCG

Honors and awards

  • Ph.D. Scholarship | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico). | 2017 - current

  • Graduate Student Mobility Scholarship (BECA MIXTA) | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico). | 2017

  • Master’s Scholarship | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico).| 2013 - 2015

  • Graduate Student Mobility Scholarship (BECA MIXTA) | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico).| 2014-2015

  • Summer Scholarship | CINVESTAV | 2013

  • Undergraduate Student Mobility Award | CINVESTAV | 2011

  • Undergraduate Scholarship | IPN | 2007-2011

Publications

Authors Title Year Journal
AB Villaseñor-Altamirano, M Moretto, M Maldonado, A Zayas-Del Moral, … PulmonDB: A curated lung disease gene expression database 2020 Scientific reports
M Bravo-Lopez, V Villa-Islas, C Rocha Arriaga, AB Villaseñor-Altamirano, … Paleogenomic insights into the red complex bacteria tannerella forsythia in pre-hispanic and colonial individuals from mexico 2020 Philosophical Transactions of the Royal Society B
M Moretto, P Sonego, AB Villaseñor-Altamirano, K Engelen First step toward gene expression data integration: Transcriptomic data acquisition with COMMAND> 2019 BMC bioinformatics
AB Villaseñor-Altamirano, JD Watson, SD Prokopec, CQ Yao, PC Boutros, … 2,3,7,8-tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver 2019 PloS one

IPN CINVESTAV UNAM

Ana Beatriz Villaseñor Altamiano

Bio

I am a Ph.D. candidate in Alejandra Medina-Rivera’s lab, the Regulatory Genomics and Bioinformatics Laboratory at International Laboratory for Human Genome Research (LIIGH) from the National Autonomous University of Mexico (UNAM). Our goal is to integrate public microarray and RNA-seq data, together with samples manually curated of lung diseases, such as Chronic Obstructive Pulmonary Disease (COPD) and Idiopatic Pulmonary Fibrosis (IPF) for better characterization of gene expression signatures. We work in close colaboration with Julio Collado-Vides, Moises Selman and Yalbi I. Balderas-Martínez.

Education

Projects

We created PulmonDB, a gene expression lung diseases database, created with public transcriptomic high-throuput data and manual curation information with an online interface for a quick accessibility.

  • Gene expression profile in COPD patients

Using PulmonDB we are analysing gene expression profiles in COPD patients to understand better the disease.

Past Projects

My project aim was to unscramble the alternative splicing effects of TCDD in C57BL6 mouse hepatocytes using high-throughput data.

I characterized the protein expression of Insulin-Like Growth Factor Binding Protein II (IGFBP2) during the develompent of cancer in rat livers using blood and tissue.

Internships

PulmonDB data analysis.

Set non-public resource to build compendia in Mexico.

Explored exon microarrays of mouse liver to characterize alternative splicing events under TCDD exposure.

Analyzed cell growth, viability, and metastasis by transfectin postate cell lines to uncover potential prostate cancer driver genes.

Seminars, conferences and workshops

  • WGCAC Next Generation Sequencing Bioinformatics Chile 2019 Workshop attendee | 2019 | Santiago, Chile

  • Statistical and Computational Challenges in High-Throughput Genomics with Application to Precision Medicine Talk | 2018 | Oaxaca, Mexico

  • American Thoracic Society 2018, International Conference Poster | 2018 | San Diego, CA

  • International Workshops on Bioinformatics-PYTHON Workshop attendee | 2017 | CCG, UNAM

Teaching

  • Ecology/R Workshop in DataCarpentry | Instructor 2018 | Universidad de Puerto Rico | 2017 | Puerto Rico, San Juan

  • International Workshops on Bioinformatics-GALAXY Teacher Assistant | Universidad Nacional Autonoma de México | 2017 | México, CCG

Honors and awards

  • Ph.D. Scholarship | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico). | 2017 - current

  • Graduate Student Mobility Scholarship (BECA MIXTA) | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico). | 2017

  • Master’s Scholarship | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico).| 2013 - 2015

  • Graduate Student Mobility Scholarship (BECA MIXTA) | Consejo Nacional de Ciencia y Tecnología (CONACYT, Mexico).| 2014-2015

  • Summer Scholarship | CINVESTAV | 2013

  • Undergraduate Student Mobility Award | CINVESTAV | 2011

  • Undergraduate Scholarship | IPN | 2007-2011

Publications

Authors Title Year Journal
AB Villaseñor-Altamirano, M Moretto, M Maldonado, A Zayas-Del Moral, … PulmonDB: A curated lung disease gene expression database 2020 Scientific reports
M Bravo-Lopez, V Villa-Islas, C Rocha Arriaga, AB Villaseñor-Altamirano, … Paleogenomic insights into the red complex bacteria tannerella forsythia in pre-hispanic and colonial individuals from mexico 2020 Philosophical Transactions of the Royal Society B
M Moretto, P Sonego, AB Villaseñor-Altamirano, K Engelen First step toward gene expression data integration: Transcriptomic data acquisition with COMMAND> 2019 BMC bioinformatics
AB Villaseñor-Altamirano, JD Watson, SD Prokopec, CQ Yao, PC Boutros, … 2,3,7,8-tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver 2019 PloS one

IPN CINVESTAV UNAM